UK edges slowly towards first trials of an AIDS vaccine

Ethical considerations in AIDS vaccine trials.

Preparedness for AIDS vaccine trials in India.

India bears a heavy disease burden of HIV/AIDS infected and affected people. A safe, effective and accessible preventive AIDS vaccine, used along with other preventive interventions, is urgently needed to stem the epidemic. This review highlights the extensive preparedness activities undertaken from 2002 by the International AIDS Vaccine Initiative (IAVI), its Indian government and non governme...

Prospects for an AIDS vaccine.

Acquired immunodeficiency syndrome (AIDS) was first identified at the end of 1981.1 In 1983, the causative virus, human immunodeficiency virus (HIV-1), was identified2, almost certainly having entered humans from a reservoir in chimpanzees, possibly on several occasions.3 Since 1981 the virus has spread to cause possibly the most serious epidemic infection in human history. The virus has divers...

AIDS vaccine trials for India: getting the facts right.

In the last several months, there have been discussions in the media, including in this journal (1), about issues related to how AIDS vaccine trials are conducted in India. The International AIDS Vaccine Initiative (IAVI) has partnered with the ministry of health and family welfare in India through the National AIDS Control Organisation (NACO) and the Indian Council of Medical Research (ICMR) s...

The Development of an AIDS Mucosal Vaccine

It is well known that mucosal tissues contain the largest surface area of the human body and are the front line of natural host defense against various pathogens. In fact, more than 80% of infectious disease pathogens probably gain entry into the susceptible human hosts through open mucosal surfaces. Human immunodeficiency virus type one (HIV-1), a mainly sexually transmitted virus, also primar...